The Louvre museum in Paris, France, is using the Nintendo 3DS as an audioguide replacement:
Usually museum audioguides are based on very expensive hardware with little (or no) multimedia features. This hardware is expensive because the vendor must have it available for 5-7 years. In technology that’s a lot of time: after the 4-5th year it’s really expensive to buy hardware components, even if those components were initially cheap.
Using a standar 3DS videoconsole, the museum can use standard hardware that is very easy to replace; and in case there is a new 3DS model, they can still use the same content without the need to port the applications and guide to the new device.